Application and advantages of medical titanium alloys in cardiovascular and cerebrovascular repair materials

Examples of the application of titanium and titanium alloys in the human cardiovascular system include artificial heart valves, blood filters, pacemakers and artificial heart pumps.

The main advantages are:

 ① High strength, good chemical stability, and excellent biocompatibility;

 ② Titanium is non-magnetic, and seldom produces false images in the magnetic resonance spectrum MRI;

 ③ The elasticity and shape recovery function of NiTi memory alloy is very suitable for medical applications. NiTi alloy is martensitic at low temperature (near zero) and can easily become a shape that is easy to be introduced into the human body. When the temperature rises to body temperature Reverse phase transition will occur at the time, so as to return to the original set shape and produce a larger restoring force for orthopedic and support. In recent years, the application of NiTi shape memory alloy in vascular stents has attracted much attention. However, NiTi alloys may dissolve Ni ions under physiological conditions, thereby inducing toxicity and inflammatory reactions. To this end, researchers have conducted a large number of surface modification studies on the alloy. The main methods include surface inert coating, surface oxidation, surface activation and surface grafting of macromolecules. Although the footholds are different, they can effectively inhibit the dissolution of Ni ions and improve the corrosion resistance and biocompatibility of NiTi alloys.

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