2020年1月14日星期二

Application of titanium and titanium alloys in the medical field

Application of titanium alloy in facial treatment
When the human face receives severe damage, local tissue repair must be treated with surgical implantation. Titanium alloy has good biocompatibility and required strength, so it becomes an ideal material for human facial tissue repair. The skull bracket made of pure titanium mesh has been widely used in jaw bone reconstruction surgery and has achieved good clinical results.
Second, the application of titanium in the pharmaceutical industry
In the pharmaceutical industry, titanium is mainly used to make containers, reactors, and heaters. During the production of pharmaceuticals, the equipment often comes into contact with hydrochloric acid, nitric acid, sulfuric acid, and other inorganic acids, organic acids, and their salts. The equipment is damaged due to long-term corrosion. At the same time, product quality is affected by iron ion pollution caused by steel equipment. Titanium equipment can solve these problems. For example, penicillin esterification kettles, saccharification tanks, chloramphenicol film evaporators, dimethyl sulfate coolers, chemical liquid filters, etc., have precedents for selecting titanium materials. The quantity and quality of the medicinal solution produced by the titanium equipment have been continuously improved, and the quality fully meets the requirements of the Chinese Pharmacopoeia.
Application of Titanium in Medical Devices
 In the history of the development of surgical instruments, the first generation of surgical instruments was mostly made of carbon steel, and because the performance of electroplated carbon steel instruments could not meet the requirements of clinical use, they were eliminated. The second generation is austenitic, ferritic, and martensitic stainless steel surgical instruments, but the chromium in stainless steel is toxic, and the detached chrome plating has a certain effect on the human body. Therefore, the third generation-titanium surgical instruments. The lightweight and high strength of titanium make it particularly suitable for microsurgery. Titanium has corrosion resistance, good elasticity, non-deformation, etc., the surface quality of repeated cleaning and disinfection will not be affected; non-magnetic can eliminate the threat of damage to small and sensitive implanted electronic devices, etc. These advantages make titanium surgical instruments more and more suitable Wider and wider. Currently, titanium has been used to make surgical blades, hemostats, scissors, electric bone drills, tweezers and more. In medical equipment, titanium blood vessel suture needles, sternum sutures, oxygen filters as one of the cardiac surgical instruments, titanium in electrodes for electrocardiography, titanium incubators in vitro culture machines, probes for medical ultrasonic pulverizers, Automatic controllers for blood transport boxes, and titanium instruments for ophthalmic surgery.
4. Dental applications of titanium and titanium alloys
 Metals used in dental surgery started from amalgam and metal crowns in the 1920s. Gold, silver, and palladium alloys were mainly used in the 1960s, and stainless steel became permanent and removable instruments for orthodontics after the 1970s. The most commonly used material, titanium casting technology was popularized in the 1990s. Dental uses titanium precision casting machine to cast with high dimensional accuracy, no bubbles, and shrinkage. Among the metal materials used for human hard tissue repair, the elastic modulus of titanium is the closest to human tissue, which can reduce metal implants and bones. Mechanical incompatibility between tissues. The thermal conductivity of titanium is the lowest among all dental restoration metal materials. Low thermal conductivity can reduce the thermal stimulation of dental pulp with crowns, which is very important for dental restorations. Titanium inlays, full crowns, etc. can protect the pulp and prevent hot and cold stimulation. In terms of materials, dental titanium is mostly pure titanium, but its strength is insufficient, it is difficult to grind, it has poor wear resistance, it is easy to produce casting defects and its quality is unstable. Titanium alloy has high strength. The most commonly used is the Ti-6Al-4V alloy. However, because metal V is harmful to the human body, Nb is used instead of V. The Ti-6Al-7Nb alloy has been successfully developed. It has excellent corrosion resistance and The human body is basically harmless, but also has other advantages such as strong plasticity and excellent abrasiveness, which has been approved by ASTM standards. At present titanium can be used as dental crowns, crown nails, fixed bridges, porcelain bridges, bonded bridges, denture rings, bases, connection devices, and reinforcement devices. Almost all metal parts of the denture can be made of titanium. Titanium alloy porcelain teeth can restore the shape and function of the tooth and have high strength, beautiful appearance, stable color, smooth surface, wear resistance and corrosion resistance. It is a permanent restoration that is suitable for all fixed teeth. In particular, it has good biocompatibility and is suitable for people who are sensitive to nickel ions. It has been widely used in dental restorations.
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